Patents
DiMarchi, Richard D. Inhibiting undesired thiol reactions during cyanogen bromide cleavage of peptides. U.S. (1984), 4 pp. CODEN: US 4451396 A 19840529 CAN 101:68926 AN 1984:468926 CAPLUS
DiMarchi, Richard Dennis; Shaar, Carl Joseph. Growth hormone release factor analogs. Eur. Pat. Appl. (1985), 33 pp. CODEN: EPXXDW EP 138416 A2 19850424 CAN 104:34340 AN 1986:34340 CAPLUS
DiMarchi, Richard Dennis; Brooke, Gerald Stephen. Synthetic vaccines for foot and mouth disease. Eur. Pat. Appl. (1986), 38 pp. CODEN: EPXXDW EP 204480 A2 19861210 CAN 107:64833 AN 1987:464833 CAPLUS
DiMarchi, Richard D. Purifying proinsulin-like materials by chromatography on Amberlite XAD resins. U.S. (1986), 5 pp. CODEN: USXXAM US 4616078 A 19861007 CAN 106:132388 AN 1987:132388 CAPLUS
DiMarchi, Richard Dennis. Inhibiting peptide carbamylation. Eur. Pat. Appl. (1986), 15 pp. CODEN: EPXXDW EP 171276 A2 19860212 CAN 105:111514 AN 1986:511514 CAPLUS
DiMarchi, R. D. (1986). Process for Inhibiting Peptide Carbamylation. U. S. Patent Number 4,605,513.
DiMarchi, R. D. and Shaar, C. J. (1986). Growth Hormone Release Factor Analogs U. S. Patent Number 4,617,149.
DiMarchi, Richard Dennis; Brooke, Gerald Stephen. Selective chemical removal of protein amino-terminal residues from biosynthetically-produced peptides. Eur. Pat. Appl. (1987), 27 pp. CODEN:EPXXDW EP 220958 A2 19870506 CAN 112:21293 AN 1990:21293 CAPLUS
DiMarchi, R. D. and Brooke, G. S. (1988). Synthetic Vaccines for Foot and Mouth Disease. U. S. Patent Number 4,732,971.
DiMarchi, Richard D.; Long, Harlan B. Process for selective peptide bond cleavage at tryptophan residues using sulfoxides and trifluoroacetic acid. U.S. (1988), 6 pp. CODEN: USXXAM US 4745178 A 19880517 CAN 110:58102 AN 1989:58102 CAPLUS
DiMarchi, R. D. and Brooke, G. S. (1988). Selective Chemical Removal of a Protein Amino-Terminal Residue. U. S. Patent Number 4,782,139.
DiMarchi, R. D. and Long, H. B. (1989). Process for Reducing Methionine Sulfoxide Residues in Peptides or Proteins. U. S. Patent Number 4,835,254.
Di Marchi, Richard Dennis; Long, Harlan Beall. Reduction of methionine sulfoxide residues in peptides and proteins. Ger. Offen. (1989), 6 pp. CODEN: GWXXBX DE 3828287 A1 19890309 CAN 111:97728 AN 1989:497728 CAPLUS
Chance, Ronald Eugene; Dimarchi, Richard Dennis; Frank, Bruce Hill; Shields, James Edwin. Preparation of insulin with modified association and biological properties.Eur. Pat. Appl. (1990), 67 pp. CODEN: EPXXDW EP 383472 A2 19900822 CAN 114:179723 AN 1991:179723 CAPLUS
DiMarchi, R. D., Heiman, M. L., Shields, J. E., Smiley, D. L., Wickister, D. I. (1991). Superactive GRFAnalogs. U. S. Patent Number 4,904,001
Brooke, Gerald Stephen; Dimarchi, Richard Dennis; Heiman, Mark Louis; Hsiung, Hansen Maxwell; Smiley, David Lee; Smith, Dennis Paul. Growth hormone releasing factor analogs and their manufacture with recombinant Escherichia coli. Eur. Pat. Appl. (1991), 39 pp. CODEN: EPXXDW EP 454367 A2 19911030 CAN 116:188664 AN 1992:188664 CAPLUS
DiMarchi, Richard Dennis; Gesellchen, Paul David; Owens, Rebecca Anne. Rapid synthesis and screening of peptide mimetics. Eur. Pat. Appl. (1992), 12 pp. CODEN: EPXXDW EP 519640 A1 19921223 CAN 119:139789 AN 1993:539789 CAPLUS
DiMarchi, Richard Dennis; Heiman, Mark Louis; Shields, James Edwin; Smiley, David Lee. Superactive growth hormone-releasing factor (GRF) analogs. Eur. Pat. Appl. (1992), 32 pp. CODEN: EPXXDW EP 511003 A1 19921028 CAN 118:184427 AN 1993:184427 CAPLUS
Belagaje, Rama M.; Dimarchi, Richard Dennis; Heath, William Francis, Jr.; Long, Harlan Beall. Proinsulin with an N-terminal A-chain and its manufacture and accurate processing in Escherichia coli. Eur. Pat. Appl. (1992), 80 pp. CODEN: EPXXDW EP 518587 A2 19921216 CAN 118:118311 AN 1993:118311 CAPLUS
DiMarchi, Richard Dennis; Kit, Saul; Little, Sheila Parks; Gale, Charles; Kit, Malon. Herpesvirus-based viral vector containing foot-and-mouth disease virus epitope and its use as a vaccine. Eur. Pat. Appl. (1992), 72 pp. CODEN: EPXXDW EP 471457 A2 19920219 CAN 117:220059 AN 1992:620059 CAPLUS
Belagaje, R., M., DiMarchi, R. D., Heath, W. F. Jr., and Long, H. B. (1994). “A-C-B Proinsulin, Method of Manufacturing and Using Same, and Intermediates in Insulin Production.” U. S. Patent Number 5,304,473.
DiMarchi, R. D., Gesellchen, P. D., and Owens, R. A. (1995). Rapid Synthesis and Screening of Peptide Mimetics. U. S. Patent Number 5,422,426.
DiMarchi, Richard Dennis; Fan, Li; Long, Harlan Beall. IGF-1 superagonists. Eur. Pat. Appl. (1996), 15 pp. CODEN: EPXXDW EP 742228 A1 19961113 CAN 126:55338 AN 1997:44641 CAPLUS
Chance, Ronald Eugene; DiMarchi, Richard Dennis; Hoffmann, James Arthur; Long, Harlan Beall; Miller, Anne Reifel. Single chain insulin analogs with high biological activity for treatment of diabetes. Eur. Pat. Appl. (1996), 22 pp. CODEN: EPXXDW EP 741188 A2 19961106 CAN 126:14767 AN 1996:748391 CAPLUS
Basinski, Margret B.; DiMarchi, Richard D.; Flora, David B.; Heath, William F., Jr.; Hoffmann, James A.; Schoner, Brigitte E.; Shields, James E.; Smiley, David L. Anti-obesity proteins. U.S. (1996), 12 pp., Cont.-in-part of U.S. Ser. No. 381, 247. CODEN: USXXAM US 5569744 A 19961029 CAN 126:2513 AN 1996:701935 CAPLUS
Basinski, Margret; DiMarchi, Richard D.; Flora, David B.; Heath, William F., Jr.; Hoffmann, James A.; Schoner, Brigitte E.; Shields, James E.; Smiley, David L. Anti-obesity proteins. U.S. (1996), 12 pp., Cont.-in-part of U.S. Ser. No. 381,047, abandoned. CODEN: USXXAM US 5567803 A 19961022 CAN 126:22877 AN 1996:679505 CAPLUS
Basinski, Margret B.; DiMarchi, Richard D.; Heath, William F., Jr.; Schoner, Brigitte E. Anti-obesity proteins, their amino acid sequences, expression in Escherichia coli, and pharmaceutical uses. U.S. (1996),13 pp., Cont.-in-part of U.S. Ser. No. 381,031, abandoned. CODEN: USXXAM US 5559208 A 19960924 CAN 125:309037 AN 1996:637440 CAPLUS
Basinski, Margaret B.; DiMarchi, Richard D.; Flora, David B.; Heath, William F., Jr.; Hoffmann, James A.; Schoner, Brigitte E.; Shields, James E.; Smiley, David L. Anti-obesity proteins and their preparation for clinical use. PCT Int. Appl. (1996), 30 pp. CODEN: PIXXD2 WO 9623516 A1 19960808 CAN 125:244218 AN 1996:601768 CAPLUS
Basinski, Margaret B.; DiMarchi, Richard D.; Heath, William F., Jr.; Schoner, Brigitte E. Cloning and formulation of antiobesity proteins. PCT Int. Appl. (1996), 33 pp. CODEN: PIXXD2 WO 9623513 A1 19960808 CAN 125:257215 AN 1996:596136 CAPLUS
Basinski, Margaret B.; DiMarchi, Richad D.; Heath, William F., Jr.; Schoner, Brigitte E. Cloning and formulation of antiobesity proteins. PCT Int. Appl. (1996), 33 pp. CODEN: PIXXD2 WO 9623519 A1 19960808 CAN 125:257212 AN 1996:596133 CAPLUS
Basinski, Margaret B.; DiMarchi, Richard D.; Heath, William F., Jr.; Schoner, Brigitte E. Antiobesity proteins. PCT Int. Appl. (1996), 33 pp. CODEN: PIXXD2 WO 9623520 A1 19960808 CAN 125:257211 AN 1996:596132 CAPLUS
Basinski, Margret B.; DiMarchi, Richard D.; Heath, William F., Jr.; Schoner, Brigitte E. Antiobesity proteins. U.S. (1996), 13 pp., Cont.-in-part of U.S. Ser. No. 381, 033, abandoned. CODEN: USXXAM US 5554727 A 19960910 CAN 125:309021 AN 1996:590816 CAPLUS
Basinski, Margret B.; DiMarchi, Richard D.; Heath, William F., Jr.; Schoner, Brigitte E. Anti-obesity proteins and pharmaceuticals containing them. U.S. (1996), 13 pp., Cont.-in-part of U.S. Ser. No. 381,661, abandoned. CODEN: USXXAM US 5552524 A 19960903 CAN 125:266029 AN 1996:577851 CAPLUS
Basinski, Margret B.; DiMarchi, Richard D.; Heath, William F., Jr.; Schoner, Brigitte E. Anti-obesity proteins and pharmaceuticals containing them. U.S. (1996), 12 pp., Cont.-in-part of U.S. Ser. No. 381,458, abandoned. CODEN: USXXAM US 5552523 A 19960903 CAN 125:266028 AN 1996:577850 CAPLUS
Basinski, Margret B.; DiMarchi, Richard D.; Flora, David B.; Hale, John E.; Heath, William F., Jr.; Hoffmann, James A.; Schoner, Brigitte E. Synthetic anti-obesity proteins more stable than mouse or human proteins, sequences, recombinant production, and pharmaceutical uses. Eur. Pat. Appl. (1996), 56 pp. CODEN: EPXXDW EP 725079 A1 19960807 CAN 125:212702 AN 1996:567261 CAPLUS
Basinsky, Margret B.; DiMarchi, Richard D.; Heath, William F., Jr.; Schoner, Brigitte E. Synthetic anti-obesity proteins more stable than mouse or human proteins, sequences, recombinant production, and pharmaceutical uses. Eur. Pat. Appl. (1996), 42 pp. CODEN: EPXXDW EP 725078 A1 19960807 CAN 125:212701 AN 1996:567260 CAPLUS
DiMarchi, Richard D.; Flora, David B.; Heath, William F., Jr.; Hoffmann, James A.; Shields, James E.; Smiley, David L. Anti-obesity proteins. U.S. (1996), 11 pp. CODEN: USXXAM US 5532336 A 19960702 CAN 125:140658 AN 1996:452794 CAPLUS
DiMarchi, Richard D.; Flora, David B.; Heath, William F., Jr.; Hoffmann, James A.; Shields, James E.; Smiley, David L. Synthesis and formulation of antiobesity proteins. U.S. (1996), 10 pp. CODEN: USXXAM US 5525705 A 19960611 CAN 125:77486 AN 1996:411078 CAPLUS
DiMarchi, Richard D.; Flora, David B.; Heath, William F., Jr.; Hoffmann, James A.; Shields, James E.; Smiley, David L. Preparation of anti-obesity proteins. U.S. (1996), 10 pp. CODEN: USXXAM US 5521283 A 19960528 CAN 125:115163 AN 1996:380239 CAPLUS
Chen, Victor John; Dimarchi, Richard D.; Kriauciunas, Aidas V.; Smiley, David L.; Stucky, Russell D. Glucagon-like insulinotropic peptide analogs and their use in diabetes treatment. Eur. Pat. Appl. (1996), 21 pp. CODEN: EPXXDW EP 708179 A2 19960424 CAN 124:307606 AN 1996:290631 CAPLUS
Chen, V. J., DiMarchi, R. D., Smiley, D. L., Stucky, R. D., and Kriauciunas, A. V. (1996). “Glucagon-like Insulinotropic Peptide Analogs, Compositions, and Methods of Use.” U. S. Patent Number 5,512,549.
Chance, R. E., DiMarchi, R. D., Frank, B. H. and Shields, J. E. (1996). “Insulin Analogs Modified at Position 29 of the B Chain.” U. S. Patent Number 5,514,646.
DiMarchi, R. D., Flora, D. B., Heath, Jr., W. F., Hoffmann, J. A., Shields, J. E.,and Smiley, D. L. (1996). Anti-obesity Proteins. U. S. Patent Number 5,521,283.
DiMarchi, R. D., Flora, D. B., Heath, Jr., W. F., Hoffmann, J. A., Shields, J. E.,and Smiley, D. L. (1996). Anti-obesity Proteins. U. S. Patent Number 5,525,705.
DiMarchi, R. D., Flora, D. B., Heath, Jr., W. F., Hoffmann, J. A., Shields, J. E. and Smiley, D. L. (1996). Anti-obesity Proteins. U. S. Patent Number 5,563,243.
DiMarchi, R. D., Flora, D. B., Heath, Jr., W. F., Hoffmann, J. A., Shields, J. E. and Smiley, D. L. (1996). Anti-obesity Proteins. U. S. Patent Number 5,563,244.
DiMarchi, R. D., Flora, D. B., Heath, Jr., W. F., Hoffmann, J. A., Shields, J. E. and Smiley, D. L. (1996). Anti-obesity Proteins. U. S. Patent Number 5,563,245.
DiMarchi, R. D., Flora, D. B., Heath Jr., W. F., Hoffmann, J. A., Shields, J. E. and Smiley, D. L. (1996). Anti-obesity Proteins. U. S. Patent Number 5,567,678.
DiMarchi, R. D., Flora, D. B., Heath, Jr., W. F., Hoffmann, J. A., Shields, J. E. and Smiley, D. L. (1996). Anti-obesity Proteins. U. S. Patent Number 5,569,743.
DiMarchi, R. D., Flora, D. B., Heath, Jr., W. F., Hoffmann, J. A., Shields, J. E. and Smiley, D. L. (1996). Anti-obesity Proteins. U. S. Patent Number 5,574,133.
DiMarchi, R. D., Flora, D. B., Heath, Jr., W. F., Hoffmann, J. A., Shields, J. E.and Smiley, D. L. (1996). Anti-obesity Proteins. U. S. Patent Number 5,580,954.
DiMarchi, R. D., Fan, L., Long, H. B. (1997). “IGF-I Superagonists.” U.S. Patent Number 5,622,932.Basinski, Margret B.; Dimarchi, Richard D.; Flora, David B.; Heath, William F., Jr.; Hoffmann, James A.; Schoner, Brigitte E.; Shields, James E.; Smiley, David L. Anti-obesity proteins. U.S. (1997), 11 pp., Cont.-in-part of U.S. Ser. No. 381,451, abandoned. CODEN: USXXAM US 5691309 A 19971125 CAN 128:30714 AN 1997:772196 CAPLUS
Borts, Tracy L.; Broderick, Carol L.; Dimarchi, Richard D.; Grinnell, Brian W.; Miller, Anne R. Glucagon-like peptide 1-based protein heterologous expression in transformed mammal cell line, gene therapy of diabetes, and transformed cell line implants. PCT Int. Appl. (1997), 30 pp. CODEN: PIXXD2 WO 9729180 A1 19970814 CAN 127:201022 AN 1997:542509 CAPLUS
Broderick, Carol L.; Dimarchi, Richard D.; Heiman, Mark L.; Stramm, Lawrence E. Method of treating insulin resistance with GH releasing agents. PCT Int. Appl. (1997), 28 pp. CODEN: PIXXD2 WO9709060 A1 19970313 CAN 126:288562 AN 1997:317749 CAPLUS
Basinski, Margret B.; Dimarchi, Richard D.; Flora, David B.; Heath, William F., Jr.; Hoffmann, James A.; Schoner, Brigitte E.; Shields, James E.; Smiley, David L. Antiobesity proteins. U.S. (1997), 12 pp., Cont.-in-part of U.S. Ser. No. 383,648, abandoned. CODEN: USXXAM US 5605886 A 19970225 CAN 126:216641 AN 1997:196177 CAPLUS
Basinski, Margret B.; Dimarchi, Richard D.; Flora, David B.; Heath, William F., Jr.; Hoffmann, James A.; Schoner, Brigitte E.; Shields, James E.; Smiley, David L. Cloning and formulation of anti-obesity proteins. U.S. (1997), 12 pp., Cont.-in-part of U.S. Ser. No. 381,266, abandoned. CODEN: USXXAM US 5594104 A 19970114 CAN 126:162223 AN 1997:97732 CAPLUS
Basinski, M. B., DiMarchi, R. D., Flora, D. B., Heath, Jr., W. F., Hoffmann, J. A., Schoner, B. E., Shields, J. E., and Smiley, D. L. (1997). Anti-obesity Proteins. U. S. Patent Number 5,691,309.
Chance, R. E., DiMarchi, R. D., Frank, B. H., and Shields, J. E. (1997). Process for Preparing Insulin Analogs. U. S. Patent Number 5,700,662,
DiMarchi, Richard D.; Efendic, Suad. Use of glucagon-like peptide-1 analogs and derivatives administered peripherally in regulation of obesity. PCT Int. Appl. (1998), 42 pp. CODEN: PIXXD2 WO 9819698 A1 19980514 CAN 129:8575 AN 1998:323152 CAPLUS
Beals, John M.; Dimarchi, Richard D. Chimpanzee leptin derivatives that do not aggregate for use as parenteral anti-obesity agents. PCT Int. Appl. (1998), 55 pp. CODEN: PIXXD2 WO 9816545 A1 19980423 CAN 128:326468 AN 1998:251188 CAPLUS
DiMarchi, Richard D.; Hermeling, Ronald N.; Hoffmann, James A. Preparation of anti-obesity proteins. U.S. (1998), 17 pp. CODEN: USXXAM US 5719266 A 19980217 CAN 128:201061 AN 1998:146588 CAPLUS
DiMarchi, R. D., Hermeling, R. N. and Hoffmann, J. A. (1998). Anti-Obesity Proteins. U. S. Patent Number 5,719,266
Basinski, M. B., DiMarchi, R. D., Flora, D. B., Heath, Jr., W. F., Hoffmann, J. A.,Schoner, B. E., Shields, J. E., and Smiley, D. L. (1998). Anti-Obesity Proteins. U. S. Patent Number 5,851.995.
DiMarchi, R.D., Harrison R.G., and Wolff, R.K Pulmonary Delivery of Insulin Analogs. U. S. Patent Application Docket P-11794. (Jan 1998)
Broderick, C. L., DiMarchi, R. D., Heiman, M. L., and Stramm, L. E. (1999). Method of Treating Insulin Resistance. U. S. Patent Number 5,939,387.
DiMarchi, Richard Dennis; Harrison, Roger Garrick; Wolff, Ronald Keith. Inhalation method for administering monomeric insulin analogs. PCT Int. Appl. (1999), 39 pp. CODEN: PIXXD2 WO 9934816 A1 19990715 CAN 131:106786 AN 1999:451201 CAPLUS
DiMarchi, Richard Dennis; Harrison, Roger Garrick; Wolff, Ronald Keith. Inhalation method for administering AspB28-human insulin. PCT Int. Appl. (1999), 41 pp.CODEN: PIXXD2 WO 9934815 A1 19990715 CAN 131:106785 AN 1999:451200 CAPLUS
DiMarchi, R.D., DeFelippis, M. R., Frank, B. H., Hines, P.A., and Lents, M. P. Cartridge Assembly for Medicament Suspensions. U. S. Patent Application Docket P-12012. (April 1999)
DiMarchi, R.D., Harrison R.G., and Wolff, R.K Pulmonary Delivery of Insulin Analogs. U. S. Patent Application Docket P-12733. (Jan 1999)
Chance, R. E., DiMarchi, R. D., and Flora, D. B. (2001). Insulin Analogs. U. S. Patent Number 6,191,102
DiMarchi, R.D., Trautmann, M. E., and DeFelippis, M. R. Biphasic Mixtures of GLP-1 and Insulin. U.S. Patent Application Docket P-14815. (Oct 2001)
DiMarchi, R.D., DeFelippis, M. R., Kohn, W.D., Micanovic R., Zhang, L., Beals, J.M., and Myers, S.R. Insulin Derivative Having Protracted Time Action. U. S. Patent Application Docket P-15012. (Dec 2001)
DiMarchi, R.D., Glaesner W., and Millican R. L. Amidated Glucagon-Like Peptide 1. U. S. Patent Application Docket P-15402. (Nov 2001)
DiMarchi, R.D., Smiley, D.E., and Zhang, L. Modified Glucagon-Like Peptide-1 Analogs. U. S. Patent Application Docket P-15642. (June 2002)
Millican, Rohn Lee, Jr.; Glaesner, Wolfgang; Dimarchi, Richard Dennis. Amidated glucagon-like peptide-1. PCT Int. Appl. (2002), 50 pp. CODEN: PIXXD2 WO 2002048192 A2 20020620 CAN 137:52331 AN 2002:466049 CAPLUS
DiMarchi, R.D., and DeFelippis, M. R. GLP-1 and Basal Insulin Mixtures. U. S. Patent Application Docket P-14314A. (May 2002)
DiMarchi, R.D., and DeFelippis, M. R. GLP-1 and Basal Insulin Mixtures. U. S. Patent Application Docket P-14314B. (June 2002)
DiMarchi, R.D., DeFelippis, M. R., and Ng, K. Pre-Mixed Formulation of GLP-1 and Basal Insulin. U. S. Patent Application Docket P-14314. (August 2002)
DiMarchi, R.D. and Efendic, S. (2003). Use of GLP-1 Analogs and Derivatives Administered Peripherally in Regulation of Obesity. U.S. Patent 6,583,111 B1
DiMarchi, R.D., Glaesner, W., Millican, R.L., Vick, A.M., and Zhang, L. Pegylated GLP-1. U. S. Patent Application Docket P-16020. (Mar 2003)
DiMarchi, Richard Dennis; Smiley, David Lee; Zhang, Lianshan. Preparation of modified glucagon- like peptide-1 analogs. PCT Int. Appl. (2003), 124 pp. CODEN: PIXXD2 WO 2003103572 A2 20031218 CAN 140:42466 AN 2003:991273 CAPLUS
DiMarchi, R.D. Insulin Analog Having Protracted Time Action. U. S. Patent Application Docket P-16270. (April 2003)
DiMarchi, R.D. Insulin Analog Having Protracted Time Action. U. S. Patent Application Docket P-16270A. (May 2003)
Beals, John Michael; Defelippis, Michael Rosario; DiMarchi, Richard Dennis; Kohn, Wayne David; Micanovic, Radmila; Myers, Sharon Ruth; Ng, Kingman; Zhang, Lianshan. Synthesis, properties, and therapeutic uses of insulin derivatives having protracted time action. PCT Int. Appl. (2003), 87 pp. CODEN: PIXXD2 WO 2003053339 A2 20030703 CAN 139:79536 AN 2003:511080 CAPLUS
Defelippis, Michael Rosario; DiMarchi, Richard Dennis; Trautmann, Michael Ernst; Ng, Kingman. Biphasic mixtures of GLP-1 and insulin. PCT Int. Appl. (2003), 62 pp. CODEN: PIXXD2 WO 2003035099 A1 20030501 CAN 138:374155 AN 2003:334931 CAPLUS
Defelippis, Michael Rosario; DiMarchi, Richard Dennis; Ng, Kingman. Premixes of GLP-1 and basal insulin. PCT Int. Appl. (2003), 75 pp. CODEN: PIXXD2 WO 2003020201 A2 20030313 CAN 138:243271 AN 2003:202411 CAPLUS
DiMarchi, Richard Dennis; Kohn, Wayne David; Zhang, Lianshan. Methods for the synthesis of insulin analogs having protracted time action and therapeutic uses thereof. PCT Int. Appl. (2004), 35 pp. CODEN: PIXXD2 WO 2004096854 A2 20041111 CAN 141:389285 AN 2004:965289 CAPLUS
DiMarchi, Richard Dennis; Glaesner, Wolfgang; Millican, Rohn Lee, Jr.; Vick, Andrew Mark; Zhang, Lianshan. Polyethylene glycol linked glucagon-like peptide-1 (GLP-1) compounds. PCT Int. Appl. (2004), 77 pp. CODEN: PIXXD2 WO 2004093823 A2 20041104 CAN 141:400875 AN 2004:927026 CAPLUS
DiMarchi, R.D. Insulin Analog Having Protracted Time Action. U. S. Patent Application Docket P-16270M. (May 2004)
Cho, H.S, Daniel, T.D., DiMarchi, R.D., Hays A., Wilson, T., Sim, B. and Litzinger, D. Modified Human Four Helical Bundle Polypeptides and Their Uses. U. S. Patent Application Docket PCT/US05/03537 (Jan 2005)
Cho, Ho Sung; Daniel, Thomas O.; DiMarchi, Richard D.; Hays, Anna-Maria; Wilson, Troy E.; Sim, Bee-cheng; Litzinger, David C. Modified human growth hormone polypeptides with improved pharmaceutical properties. U.S. Pat. Appl. Publ. (2005), 119 pp. CODEN: USXXCO US 2005170404 A1 20050804 CAN 143:179642 AN 2005:6982
Sim, Bee-Cheng; Litzinger, David C.; Cho, Ho Sung; Daniel, Thomas O.; DiMarchi, Richard D.; Hays, Anna-Maria; Wilson, Troy E. Modified human growth hormone polypeptides with improved pharmaceutical properties. PCT Int. Appl. (2006), 337 pp. CODEN: PIXXD2 WO 2006/069220 A2 20060629 CAN 145:89716 AN 2006:633792 CAPLUS
DiMarchi, Richard D.; Smiley, David L. Glucagon analogs exhibiting physiological solubility and stability for treating hypoglycemia and weight gain. PCT Int. Appl. (2007), 2007/056362 65pp.
Day, Jonathan; Patterson, James; Chabenne, Joseph; DiMarchi, Maria; Smiley, David; Dimarchi, Richard D.. Preparation of modified glucagons as therapeutic glucagon/GLP-1 receptor co-agonists with improved solubility and stability. PCT Int. Appl. (2008),
DiMarchi, Richard D.; DiMarchi, Maria; Chabenne, Joseph. C-terminal substitution analogs of glucagon with improved solubility at physiological pH. PCT Int. Appl. 2008/086086 56pp.
Sheffer, Joseph; Norman, Thea; Dimarchi, Richard D.; Putnam, Anna-Maria A. Hays; Feng, Tian; Chu, Stephanie; Krawitz, Denise; Cho, Ho Sung. Modified human plasma polypeptide or Fc scaffolds as carriers for modulating half-life and/or immunogenicity of therapeutic molecules in circulation or serum. PCT Int. Appl. (2008), 240pp.
Day, Jonathan; Patterson, James; Chabenne, Joseph; DiMarchi, Maria; Smiley, David; Dimarchi, Richard D. Preparation of modified glucagons as therapeutic glucagon/GLP-1 receptor co-agonists with improved solubility and stability. PCT Int. Appl. 2008/101017,
DiMarchi, Richard D.; DiMarchi, Maria; Chabenne, Joseph. C-terminal substitution analogs of glucagon with improved solubility at physiological pH. PCT Int. Appl. (2008), 56pp.
Sheffer, Joseph; Norman, Thea; Dimarchi, Richard D.; Putnam, Anna-Maria A. Hays; Feng, Tian; Chu, Stephanie; Krawitz, Denise; Cho, Ho Sung. Modified human plasma polypeptide or Fc scaffolds as carriers for modulating half-life and/or immunogenicity of therapeutic molecules in circulation or serum. PCT Int. Appl. (2008), 240pp.
Richard DiMarchi, and Ma Tao, GIP-Based Peptides, U.S. Patent Application No. 61/073,274, filed 17 June 2008.
Richard DiMarchi, Ma Tao, GIP-Based Peptides, U.S. Patent Application No. 61/078,171, filed 3 July 2008.
Richard DiMarchi, Ma Tao, GIP-Based Mixed Agonists, U.S. Patent Application No. 61/090,448, filed 20 August 2008.
Richard DiMarchi, Ma Tao, GIP-Based Mixed Agonists, U.S. Patent Application No. 61/151,349, filed 10 February 2009.
Richard DiMarchi, Ma Tao, GIP-Based Mixed Agonists for Treatment of Metabolic Disorders and Obesity, International Patent Application No. PCT/US2009/47447, filed 16 June 2009
Richard DiMarchi, David Smiley, Maria DiMarchi, Joseph Chabenne, Jonathan Day, James Patterson, Brian Ward, Ma Tao, GIP Receptor-Active [analog] Compounds,U.S. Patent Application No. 61/187,578, file 16 June 2009.
DiMarchi, Richard; Yang, Bin. Preparation of peptides as glucagon antagonists. PCT Int. Appl. (2009), 127 pp. CODEN: PIXXD2 WO 2009058662 A2 20090507 CAN 150:515462 AN 2009:553416 CAPLUS
DiMarchi, Richard D.; Yang, Bin; Ouyang, Chenguang. Preparation of peptides exhibiting glucagon antagonist and GLP-1 agonist activity. PCT Int. Appl. (2009), 171 pp. CODEN: PIXXD2 WO 2009058734 A1 20090507 CAN 150:515461 AN 2009:552639 CAPLUS
DiMarchi, Richard D.; De, Arnab. Dipeptide ester-based bioactive peptide prodrugs with improved biological half-lives. PCT Int. Appl. 2009/099763 309pp.
DiMarchi, Richard D; Smiley, David L; DiMarchi, Maria; Chabenne, Joseph; Day, Jonathan. Glucagon analogs exhibiting enhanced solubility and stability in physiological pH buffers. PCT Int. Appl. 2009/155257, 165 pp.
DiMarchi, Richard D; Smiley, David L; DiMarchi, Maria; Chabenne, Joseph; Day, Jonathan; Patterson, James; Ward, Brian C. Glucagon/GLP-1 receptor co-agonists. PCT Int. Appl. 2009/155258 241 pp.
DiMarchi, Richard D.; Smiley, David L. Glucagon analogs exhibiting physiological solubility and stability. US Patent (2009), 137456 A1
DiMarchi, Richard D.; Tao, Ma. Glucagon peptides with GIP and GLP-1 agonist effects for treatment of metabolic disorders and obesity. PCT Int. Appl. 2010/011439, 213 pp.
DiMarchi, Richard D.; Kou, Binbin. Amide Based Glucagon Superfamily Peptide Prodrugs. PCT Int. Appl. 2010/071807, 311 pp.
DiMarchi, Richard D.; Han, Jie. Insulin Analogs. PCT Int. Appl. 2010/080606, 45 pp.
DiMarchi, Richard D.; Cheng, Shujiang; Kou, Binbin; Han, Jie. YL Based Insulin-Like Growth Factors Exhibiting High Activity at the Insulin Receptor. PCT Int. Appl. 2010/080607, 181 pp.
DiMarchi, Richard D.; Cheng, Shujiang; Kou, Binbin Amide Based Insulin Prodrugs. PCT Int. Appl. 2010/080609, 169 pp.
DiMarchi, Richard Dipeptide-Linked Medicinal Agents. PCT Int. Appl. 2010/080605, 98 pp.
DiMarchi, Richard D.; DiMarchi, Maria; Chabenne, Joseph Glucagon Analogs Exhibiting Enhanced Solubility in Physiological pH Buffers. US Patent Appl. (2010), 190699 A1
Day, Jonathan; Patterson, James; Chabenne, Joseph; DiMarchi, Maria; Smiley, David; DiMarchi, Richard D. Glucagon/GLP-1 Receptor Co-Agonists. US Patent Appl. (2010), 190701 A1
Bianchi, E.; Carrington, P.E.; Eiermann, G.J.; Ingallinella, P.; Marsh, D.J.; Metzer, J.M.; Pessi, A.; Pocai, A.; Sinha Roy, R.; Santoprete, A.; Cipito, E.; DiMarchi, R.; Ward, B. Oxyntomodulin Analogs. PCT Int. Appl. 2010/096052 123 pp.
Carrington, P.E.; Eiermann, Marsh, D.J.; Metzer, J.M.; Pocai, A.; Sinha Roy, R.; Bianchi, E.; Ingallinella, P.; Pessi, A.; Santoprete, A.; Cipito, E.; DiMarchi, R.; Ward, B. Oxyntomodulin Analogs. PCT Int. Appl. 2010/096142 125 pp.
Richard DiMarchi, David Smiley, Maria DiMarchi, Joseph Chabenne, Jonathan Day, James Patterson, Brian Ward, Ma Tao, GIP Receptor-Active Glucagon Compounds. PCT Int. Appl. 2010/148089 A1 262 pp.
DiMarchi, Richard D.; De, Arnab. Ester-Based Insulin Prodrugs. US Patent Appl. (2010), 0331246 A1.
DiMarchi, Richard D.; De, Arnab. Ester-Based Peptide Prodrugs. US Patent Appl. (2011), 0065633 A1.
DiMarchi, Richard D.; Yang, Bin; Ouyang, Chenguang. Compounds Exhibiting Glucagon Antagonist and GLP-1 Agonist Activity. US Patent Appl. (2011), 0098217 A1.
DiMarchi, R. Glucagon/GLP-1 Receptor Co-Agonists. PCT Int. Appl. 2011/075393 A2 129 pp.
Richard DiMarchi, Ma Tao, GIP-Based Mixed Agonists For Treatment of Metabolic Diseases and Obesity, U.S. Patent Appl. (2011), 166062 A1
Richard DiMarchi, David Smiley, Maria DiMarchi, Joseph Chabenne, Jonathan Day, Glucagon Analogs Exhibiting Enhanced Solubility in Physiological pH Buffers. US Patent Appl. (2011), 190200 A1
Richard DiMarchi, Ma Tao, Glucagon Antagonist/GIP Agonist Conjugates and Compositions For Treatment of Metabolic Diseases and Obesity, PCT Int. Appl. 2011/094337 A2 275 pp.
DiMarchi, Richard Dipeptide-Linked Medicinal Agents. US Patent Appl. (2011), 0237493 A1
DiMarchi, Richard D.; Cheng, Shujiang; Kou, Binbin; Han, Jie. YL Based Insulin-Like Growth Factors Exhibiting High Activity at the Insulin Receptor. US Patent Appl. (2011), 0245164
DiMarchi, Richard D.; Han, Jie. Insulin Analogs. US Patent. Appl. (2011) 0257091
DiMarchi, Richard D.; Cheng, Shujiang; Kou, Binbin Amide Based Insulin Prodrugs. US Patent. Appl. (2011) 257076
Richard DiMarchi; Lianshan Zhang Glucagon Superfamily Peptides Exhibiting G Protein-Coupled Receptor Activity, PCT Int. Appl. 2011/143208 A1 327 pp.
Richard DiMarchi; Bin Yang; Brian Finan Glucagon Superfamily Peptides Nuclear Hormone Receptor Activity, PCT Int. Appl. 2011/143209 A1 416 pp.
DiMarchi, Richard D.; Kou, Binbin. Amide Based Glucagon Superfamily Peptide Prodrugs. US Patent. Appl. (2011) 0288003 A1
Richard DiMarchi; Jie Han; Piotr Mroz. Novel Stable Insulin Analogs, PCT Int. Appl. 2011/159882 A2 261 pp.
Richard DiMarchi; Julia Azriel; Zach Kaur; Jonathan Meyers; Todd Parody; Yan Zhao. Single Chain Insulin Analogs Exhibiting High Activity at the Insulin Receptor, PCT Int. Appl. 2011/159895 A2 257 pp.
DiMarchi, Richard Dipeptide-Linked Medicinal Agents. PCT Int. Appl. 2011/162968 A1 183 pp.
DiMarchi, Richard D.; Cheng, Shujiang; Kou, Binbin; Han, Jie. YL Based Insulin-Like Growth Factors Exhibiting High Activity at the Insulin Receptor. PCT Int. Appl. 2011/163460 A1 310 pp.
Richard DiMarchi, Maria DiMarchi, Joseph Chabenne, Glucagon Analogs Exhibiting Enhanced Solubility and Stability in Physiological pH Buffers PCT Int. Appl. 2011/163473 A1 164 pp.
